Living Function-Resilient Society in the Centenarian Era: Living Safety Technology Based on Connective, Artificial Intelligence

In the centenarian era, it has become even more imperative to address the physical and cognitive changes faced by children, the elderly, and disabled persons. We need a “living function resilient society,” which ensures they enjoy safe living environments in ways that allow them to maintain active social participation levels despite the changes. To build such a society, more attention should be paid to problems: diversity in life function and intervention needs, gap between efficacy and effectiveness, fragmentation of living data and support service and variety in privacy exposure. To deal with these issues, this chapter describes a new approach referred to as “connective AI” that allows individual lives to be connected with each other and efficacy to be scaled to effectiveness by computerizing places of living in accordance with the private policy of individual facilities and connecting them with each other through a network. As a concrete example of connective AI, this chapter introduces smart living labs that are developed by the National Institute of Advanced Industrial Science and Technology (AIST) in cooperation with children’s hospitals, rehabilitation hospitals, intensive care homes for the elderly, and private homes

Musical combinatorics, tonnetz, and the CubeHarmonic

In this paper, we give an overview of some applications of combinatorics and permutations in music through the centuries. The concepts of permutation and tonnetz (spatial representation of voice leading and modulation) can be joined together in a physical device, the CubeHarmonic, a musical version of the Rubik’s cube. We finally describe a prototype of the CubeHarmonic that uses the magnetic tracking technology developed at the Tohoku University

Cubeharmonic: A New Interface From A Magnetic 3D Motion Tracking System To Music Performance

We developed a new musical interface, CubeHarmonic, with the magnetic 3D motion tracking system IM3D. This system precisely tracks positions of tiny, wireless, battery-less, and identifiable markers (LC coils) in real time. The CubeHarmonic is a musical application of the Rubik’s cube, with notes on each little piece. Scrambling the cube, we get different chords and chord sequences. Positions of the pieces which contain LC coils are detected through IM3D, and transmitted to the computer to recognize the status of the Rubik’s cube, that plays sounds. The central position of the cube is also measured by the LC coils located into the corners of Rubik’s cube, and, depending on the position, we can manipulate overall loudness and pitch changes, as in theremin playing. This new instrument, whose first idea comes from mathematical theory of music, can be used as a teaching tool both for math (group theory) and music (music theory, mathematical music theory), as well as a composition device, a new instrument for avant-garde performances, and a recreational tool

Online Neural Path Guiding with Normalized Anisotropic Spherical Gaussians

The variance reduction speed of physically-based rendering is heavily affected by the adopted importance sampling technique. In this paper we propose a novel online framework to learn the spatial-varying density model with a single small neural network using stochastic ray samples. To achieve this task, we propose a novel closed-form density model called the normalized anisotropic spherical gaussian mixture, that can express complex irradiance fields with a small number of parameters. Our framework learns the distribution in a progressive manner and does not need any warm-up phases. Due to the compact and expressive representation of our density model, our framework can be implemented entirely on the GPU, allowing it produce high quality images with limited computational resources

Musical combinatorics, tonnetz, and the CubeHarmonic

In this paper, we give an overview of some applications of combinatorics and permutations in music through the centuries. The concepts of permutation and tonnetz (spatial representation of voice leading and modulation) can be joined together in a physical device, the CubeHarmonic, a musical version of the Rubik's cube. We finally describe a prototype of the CubeHarmonic that uses the magnetic tracking technology developed at the Tohoku University

上皮成長因子受容体を標的とした結腸直腸腫瘍の分子イメージング : 動物モデルにおける腫瘍の検出と治療評価

To overcome the problem of overlooking colorectal tumors, a new and highly sensitive modality of colonoscopy is needed. Moreover, it is also important to establish a new modality to evaluate viable tumor volume in primary lesions of colorectal cancer (CRC) during chemotherapy. Therefore, we carried out molecular imaging of colorectal tumors targeting epidermal growth factor receptor (EGFR), which is highly expressed on tumor cells, for evaluating chemotherapeutic efficacy and for endoscopic detection of colorectal adenomas. We first attempted to image five CRC cell lines with various levels of EGFR expression using an Alexa Fluor‐labeled anti‐EGFR monoclonal antibody (AF‐EGFR‐Ab). A strong fluorescence signal was observed in the cells depending on the level of EGFR expression. When nude mice xenografted with LIM1215 CRC cells, which highly express EGFR, were i.v. injected with AF‐EGFR‐Ab, a strong fluorescence signal appeared in the tumor with a high signal to noise ratio, peaking at 48 hours after injection and then gradually decreasing, as shown using an IVIS Spectrum system. When the xenografted mice were treated with 5‐fluorouracil, fluorescence intensity in the tumor decreased in proportion to the viable tumor cell volume. Moreover, when the colorectum of azoxymethane‐treated rats was observed using a thin fluorescent endoscope with AF‐EGFR‐Ab, all 10 small colorectal adenomas (≤3 mm) were detected with a clear fluorescence signal. These preliminary results of animal experiments suggest that EGFR‐targeted fluorescent molecular imaging may be useful for quantitatively evaluating cell viability in CRC during chemotherapy, and also for detecting small adenomas using a fluorescent endoscope